Lipitor and Lipitor's Functions
Similar to many other
medicines that aim at lowering one’s cholesterol
level, Lipitor (Atorvastatin) is one. However,
its structure and functions are considerably different
to other cholesterol-lowering medicines.
Lipitor inhibits the production
of cholesterol. It is used to reduce amounts of
LDL cholesterol, total cholesterol, triglycerides,
and apolipoprotein B. Lipitor also elevates the
level of HDL cholesterol in the blood. Both these
functions of Lipitor help in reducing hardening
of arteries.
This means that heart attacks risk
is cut down. Also, strokes, and peripheral vascular
disease is reduced significantly In addition to
the purposes for which Lipitor is recommended
her, it may be used for others.
Lipitor (Atorvastatin calcium) is
an artificial lipid-lowering medicine. It inhibits
3 hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA)
reductase. Its function is to breakdown the conversion
of HMG-CoA to mevalonate; it is an initial and
rate-reducing step in cholesterol construction.
Lipitor Construction Is As Follows
[R-(R*,R*)]-2-(4-fluorophenyl)-b,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4
[(phenylamino)carbonyl]-lH-pyrrole-1-heptanoic
acid, calcium salt (2:1) trihydrate.
The Basic Chemical Formula Of Lipitor Is As Follows
(C33H34FN2O5)2Ca•3H2O
and its molecular weight is 1209.42 (Description,
2004).
Lipitor is a shade between white
and off-white. It is a crystalline powder that
does not dissolve in aqueous solutions that have
a pH of less than 4. Lipitor is however soluble
in distilled water, pH 7.4 with a phosphate buffer.
It is also soluble in acetonitrile, a shade soluble
in ethanol, and completely dissolves in methanol. |