Ortho Tricyclen: Side Effects, Interactions and Information
Ortho
Tri-Cyclen is believed to improve acne by increasing
sex hormone-binding globulin and by secondarily
causing a reduction in the plasma concentration
of free testosterone.
Therefore, it is expected to be
of particular benefit in women whose acne appears
to be related to androgen excess or hypersensitivity,
such as those who report experiencing perimenstrual
flares of their skin condition.
According to the manufacturer,
norgestimate is associated with a low rate of
nuisance adverse effects, such as weight gain,
acne, and facial hair growth.
Adverse events observed in the
women taking the birth control pill were similar
to those previously recognized in women using
the drug for oral contraception. Premenstrual
breast tenderness was the most commonly reported
side effect by her cohort of patients.
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Dermatologists have long recognized
that some women using oral contraceptives experience
improvements in their acne, but different oral
contraceptives seem to vary in their antiacne
effects, probably due to differences in the
androgenic activities of their progestin component.
These data from a well-controlled
study confirm our clinical impression that oral
contraceptives may be useful and may also establish
the efficacy of one specific product.
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The dosage and administration,
contraindications, and precautions and warnings
relevant to the use of Ortho
Tri-Cyclen as an oral contraceptive also
apply to women being treated for acne.
Patients and their physicians must
be alert to the early warning signals for potential
serious adverse effects so that the medication
can be promptly discontinued when appropriate.
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